by Publishing House of the Slovak Academy of Sciences in Bratislava .
Written in English
Includes bibliographies and index.
|Statement||organized by the Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Czechoslovakia, held at Smolenice Castle, June 19-23, 1978 ; edited by J. Zelinka and J. Balan.|
|Contributions||Zelinka, J., Balan, J., Slovenská akadémia vied. Institute of Molecular Biology.|
|LC Classifications||QP624 .I57 1978|
|The Physical Object|
|Pagination||464 p. :|
|Number of Pages||464|
|LC Control Number||80476541|
• Ribosomes are the sites of protein synthesis - they consist of ribosomal DNA (65%) and proteins (35%) NUCLEIC ACID METABOLISM: ABN mRNA Codons and Associated Amino Acids Friday, Novem 36 NUCLEIC ACID METABOLISM: ABN Reading the Genetic Code. Nonspecific interactions between enzymes involved in nucleic acid metabolism and the nucleic acids play a fundamental role in the transmission of genetic information from one cell generation to . Abstract. We have reviewed studies on the metabolism of nucleic acids and proteins which occurs during germination in order to compare the ways in which protein synthesis is modulated in a wide range of fungal spores parasitic on higher by: 4. Nucleic acid - Nucleic acid - Ribosomal RNA (rRNA): Ribosomal RNA (rRNA) molecules are the structural components of the ribosome. The rRNAs form extensive secondary structures and play an active role in recognizing conserved portions of mRNAs and tRNAs. They also assist with the catalysis of protein synthesis. In the prokaryote E. coli, seven copies of the rRNA genes synthesize ab
Nucleic Acids Book. A free online book on the chemistry and biology of nucleic acids, written by Prof. Tom Brown and Dr Tom Brown (Jnr). The book is ideal for chemistry and biology students and also provides practical information for researchers working in the lab. Nucleic acid structure. Fig 5 Folic acid metabolism. Sulfanilamide. Trimethoprim. Methotrexate. Amino salicylic acid. Dapsone. Isoniazid: Antimetabolite Antimicrobials. Inhibitors of Folic Acid Synthesis The selectivity of these antimicrobials is a consequence of the fact that bacteria cannot use pre-formed folic acid and must synthesize their own folic acid. Nucleic acid - Nucleic acid - Nucleic acid metabolism: Replication, repair, and recombination—the three main processes of DNA metabolism—are carried out by specialized machinery within the cell. DNA must be replicated accurately in order to ensure the integrity of the genetic code. Errors that creep in during replication or because of damage after replication must be repaired. Nucleic acid metabolism is the process by which nucleic acids (DNA and RNA) are synthesized and c acids are polymers of tide synthesis is an anabolic mechanism generally involving the chemical reaction of phosphate, pentose sugar, and a nitrogenous ction of nucleic acid is a catabolic reaction. Additionally, parts of the nucleotides or .
Here, we report that different variants in RPL9, a gene that has not been definitively described in DBA or other human diseases, drive similar defects in the processing of pre-rRNA during ribosome biogenesis yet reveal markedly different downstream effects on the TP53 pathway, erythrocyte development, metabolism, and the ability of ribosomes to. Irreversible ribosome stalling induces active splitting and rescue of ribosome subunits, and degradation of the incomplete protein product (Figure 3). Under these conditions, the ASC-1 helicase complex (Slh1/Rqt2 in yeast) or the recycling factors Pelota, HBS1L (or GTPBP2) and ABCE1 (Dom34, Hbs1 and Rli1 in yeast) split the stalled ribosome. Whole-genome expression profiling has provided exciting insights into the global response of M. tuberculosis to DNA damage. The development of increasingly powerful technologies for exploring protein function, structure, and expression in M. tuberculosis has led to a quantum leap in understanding nucleic acid metabolism in this organism. This chapter deals with the capacity of trace élément» to produce complexes with nucleic acids, and to modify the physical properties, structure and biological functions of nucleic acids and ribosomes. First their involvement in the function of the enzymes of nucleic acid metabolism will .